Strong Repair, Full Anti-Aging - Olive Ceramide Refreshes the Perception of Efficacy

Strong Repair, Full Anti-Aging - Olive Ceramide Refreshes the Perception of Efficacy

Olive Ceramide is the first original plant-derived ceramide developed by Dieckmann Biotechnology. At the beginning of the market, Olive Ceramide was thought to be a mixture of olive oil and ceramide, and its effects were only a superposition of the effects of olive oil and ceramide. In fact, Olive Ceramide is a kind of ceramide constructed from the fatty acids of olive oil, known as the "Queen of Vegetable Oils", and phytosphingosine through the amide bond, which is a new substance prepared through modern drug synthesis technology, rather than a physical mixture.

According to the naming rules of ceramide, each component of Olive Ceramide belongs to the NP series of ceramide, with oleic acid ceramide, linoleic acid ceramide, palmitic acid ceramide, stearic acid ceramide, and linolenic acid ceramide as its main ingredients, and may also contain other trace amounts of ceramide, which serve as efficacy supplements. So Olive Ceramide contains five or more NP ceramide.

Olive ceramide, with the concept of green and natural, belongs to the natural ceramide derivatives, and its composition and its ratio continue the natural composition ratio of olive oil fatty acids, this natural golden ratio has a synergistic effect, with bionic advantages. At the same time, the continuation of the brand story of olive oil is another upgrading and remodeling of the brand products, renewing the brand vitality.

【Olive Ceramide·Strong Repair】

Cell proliferation/cell migration/anti-inflammatory repair

1. MTT method to detect the proliferation activity of compounds on cells

Olive ceramide shows obvious effect in promoting cell proliferation and has good tissue repair ability. And significantly better than ceramide 3B.

2. Cell migration to assess the role of skin barrier repair

Olive ceramide significantly enhanced the rate of cell healing, and the healing effect was significantly better than that of Ceramide 3B. The 24h healing rate of Olive ceramide was 74.48%, and the 24h healing rate of ceramide 3B was 59.32%.

3, LPS induced cell method to detect anti-inflammatory repair efficacy

In the presence of Olive ceramide, IL-6 factor levels were significantly reduced in a dose-dependent manner, which demonstrates that Olive ceramide have a favorable anti-inflammatory effect and can promote the repair of inflammation-damaged skin.

【 Olive ceramide · Full anti-aging 】

Whitening/antioxidant/anti-photo-aging/collagen production promotion

1. Elastase inhibition experiments to test anti-aging effects       

Olive ceramide showed good inhibition of elastase at different concentrations.

 2. Inhibition of MMP-1 tests collagen and elastin synthesis in fibroblasts

MMP-1, also known as matrix metalloproteinase, whose main substrate of action is fibrillar collagen, can degrade collagen fibers and gelatin in the extracellular matrix and change the cellular microenvironment. Olive ceramide has a significant inhibitory effect on MMP-1 and promotes collagen and elastin synthesis in fibroblasts.

3. UVA, UVB ultraviolet radiation test anti-light aging effect

After UVA and UVB ultraviolet radiation, keratinocytes promote the elevated expression of MMP-1 in fibroblasts, which causes degradation of skin extracellular matrix and skin collagen, leading to skin photoaging. The above results suggest that Olive ceramide can inhibit the production of MMP-1 by fibroblasts caused by UV radiation, which is effective in preventing skin photoaging.

4, DPPH free radical scavenging assay antioxidant properties

The DPPH radical scavenging rate at 800 mg/L was 67.01%, showing excellent antioxidant effects. The DPPH radical scavenging rate of Ceramide 3B was 33.16%. The scavenging rate of DPPH by Olive ceramide was twice as high as that of Ceramide 3B, which had a better antioxidant effect.

5、Whitening activity test

100mg/L of Olive ceramide significantly inhibited melanin to 96.28%, Olive ceramide showed a good whitening effect.

【Dieckmann's Olive Ceramide 】

A pioneering exploration of efficacy                                                                  

Olive Ceramide, China's first plant-sourced ceramide, has a combination of more than five NPs. Compared with Ceramide 3 and 3B, Olive Ceramide has a stronger barrier-repairing ability and good anti-inflammatory and restorative effects. It refreshes our knowledge of plant-derived ceramides.

Olive ceramide's remarkable whitening, antioxidant, anti-photo-aging, collagen and elastin production, and comprehensive anti-aging effect is a historic breakthrough in the field of ceramides, "all-around anti-aging" taking ceramide to a new level.

Dieckmann's 2.0% Olive Ceramide Nanoemulsion

In order to better utilize olive ceramides in different formulation dosage forms and to better utilize the Olive ceramide efficacy, Dieckmann launched 2.0% olive ceramide nanoemulsion (trade name: Olive NanoCer) and endowed it with the characteristics of nanoemulsion, high skin friendliness, and high permeability.

2.0% Olive Ceramide Nanoemulsion is suitable for a variety of anti-aging and sunscreen formulation forms that not only strengthen the skin barrier repair function but also have a multi-functional all-around anti-aging effect, showing moisturizing and brightening the skin, lightening fine lines, minimizing pores, and refining and smoothing the application effect.

Dieckmann— Let the world revisit ceramide

The only olive ceramide developer in China (who has applied for a patent for invention), the only one who has solved the basic efficacy testing method of Olive ceramide, the only one who has developed the comprehensive anti-aging efficacy of ceramide, and who has made the world re-examine ceramide.